Jean-Claude Bradley and coworkers has pioneered the concept of Open Science in chemistry – and it goes beyond that. On UsefulChem he writes:
The fact that Alicia’s masters thesis “Synthesis of Diketopiperazines, Possible Malaria Enoyl Reducatase Inhibitors Using Open Source Science” is being written on a wiki was noted by Pharyngula, A Blog around the Clock and Pimm – Partial Immortalization.
I am particularly happy that Attila from Pimm has obtained permission from his supervisor to write at least part of his thesis on his blog. Outside of the sciences, I recall Mark Wagner doing something similar for his thesis on educational gaming. Also see Laura Blankenship‘s thesis on blogging in the classroom.
Yes – there has been a lot of interest in this innovative approach and I’m delighted to echo it. Since they wish this to be an open process here are my comments directly for Alicia to use if she wishes:
- I didn’t see any license on the thesis. I’m hoping it is Creative Commons sharealike (like J-C’s blog) but it’s not explicit. If that is confirmed I can highlight the thesis at Uppsala next week
- Do all the molecules have machine-readable connection tables? I noticed some that link through to SMILES – but do they all? And it would be useful to have InChIs so we could search the thesis.
- Much of the data is rendered as bitmaps of rather low quality. Could we have the reaction schemes and particularly the spectra in greater clarity. (Obviously I’d prefer CML or SVG or JCAMP… )
My immediate technical goal would be the creation of a datument (everything in XML) for the thesis – I’m not going to do all that myself. But I would be keen to see the reaction sequences in animated SVG…
The same goes, of course, for anyone else writing Open theses.